I-49 through I-64 and Signed Branch Routes

Interstate South/West Terminus North/East Terminus
49 Lafayette, LA Kansas City, MO
55 LaPlace, LA Chicago, IL
155 IL Lincoln Morton
155 MO/TN Hayti, MO Dyersburg, TN
255 MO/IL Mehlville, MO Pontoon Beach, IL
355 IL New Lenox Itasca
555 AR Turrell Jonesboro
57 Sikeston, MO (Little Rock, AR) Chicago, IL
59 Slidell, LA Wildwood, GA
359 AL Tuscaloosa Tuscaloosa
459 AL Bessemer Trussville
759 AL Attalla Gadsden
64 Wentzville, MO Chesapeake, VA
264 KY Louisville Northfield
264 VA Chesapeake Virginia Beach
464 VA Chesapeake Norfolk
564 VA Norfolk Norfolk
664 VA Chesapeake Newport News
I-55 north at Crump Bl - Memphis, TN
Interstate 55 northbound makes a TOTSO (turn of to stay on) movement along a two-lane loop ramp at the cloverleaf interchange with Crump Boulevard and Riverside Drive in Memphis, Tennessee. 05/03/12

Future roadwork by the Tennessee Department of Transportation (TDOT) will amend the substandard design of the mid-1960s cloverleaf at I-55 and Crump Boulevard with construction of a new mainline that bypasses the ramps with Crump Boulevard and Riverside Drive.

I-264 east at I-64 - Virginia Beach, VA
Interstate 264 east at I-64 in Virginia Beach, Virginia. 07/28/13

Interstate 64 is unique in the Interstate system as the easternmost 16 miles encircle Norfolk and Portsmouth, Virginia to the south and west. The Virginia Department of Transportation (VDOT) omits cardinal direction banners for the Hampton Roads Beltway between I-264/664 at Bowers Hill and I-264 at Virginia Beach.