South Carolina Interstate Routes

12 routes.

I-10 East at Interstate 20 near Kent, Texas Interstate 20 U.S. 17 North at the beginning of Interstate 26 in Charleston, South Carolina Interstate 26 I-90 West at Interstate 77 in Cleveland, Ohio Interstate 77 I-65 North at Interstate 85 in Montgomery, Alabama Interstate 85 Interstate 95 North in Miami, Florida Interstate 95 U.S. 21/176/321 North at Interstate 126 in Columbia, South Carolina Interstate 126 South Carolina U.S. 29 south where Interstate 185 begins in Greenville, South Carolina Interstate 185 South Carolina Interstate 326 proposed on the 1980 S.C. Official Highway Map Former Interstate 326 South Carolina The southbound beginning of Interstate 385 in Greenville, South Carolina Interstate 385 South Carolina I-20 East at Interstate 520 in Augusta, Georgia Interstate 520 Georgia / South Carolina The Westbound beginning of Interstate 526 from Business Spur I-526 in Mount Pleasant, South Carolina Interstate 526 South Carolina Business Loop I-85 North at Interstate 585 and U.S. 176 near Lone Oak, South Carolina Interstate 585 South Carolina