Puerto Rico Interstate System

Primary Highway 22 west at the beginning of Puerto Rico Interstate 1 Interstate PR1 Ponce, PR ↔ San Juan. PR Primary Highway 2 east at PR 52/Puerto Rico Interstate 2 Interstate PR2 Ponce. PR ↔ San Juan, PR Primary Highway 30 east at I-PR3 and PR 53 near Humacao Interstate PR3 Humacaco, PR ↔ San Juan, PR