Business Loop I-55 - New Madrid

The 5.75 mile route of Business Loop I-55 through Madrid overlays U.S. 61/62 east from Interstate 55. The route combines with U.S. 61/62 east from Exit 44 and Howardville to run along the west side of the New Madrid residential area. Mott and Mill Streets stem east from the business loop to the city center as the three routes turn northward to rejoin I-55 at Exit 49.

Updated August 1, 2026