Business Loop I-35 - Pearsall
Interstate 35 circumvents the Frio County seat of Pearsall and neighboring West Pearsall to the west. Business Loop I-35 provides a direct route to the city center from Exit 99 northeast along overlaps with FM 1581 and FM 140 (Comal Street). Overtaking old U.S. 81 along Oak Street, the business route advances northward by West Pearsall to end at Exit 104. The 5.45 mile loop was designated on March 26, 1991, partially with a mileage transfer from U.S. 81.
Updated July 31, 2026