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Interstate 76 has two business loops on its western (Colorado) section, and one connecting spur route in New Jersey (I-76C).

| COLORADO
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| Keenesburg
| Active/Unsigned
| There is an unsigned Business Spur I-76 at Keenesburg, which goes from Exit 39 south for 0.296mi/0.476km to the center of town at Old U.S. 6. |
| Fort Morgan / Brush / Sterling
| Active
| The longest continuously signed Interstate business loop follows U.S. 6 between Fort Morgan and Sterling via Brush, Hillrose, Merino, and Atwood. Running from Interstate 76 Exit 75 all the way to Exit 125, this business loop has approximately 50 miles worth of continuous signage. (The other contender for longest loop could have been Business Loop I-5 in the north Central Valley from Williams to Willows south of Red Bluff, but there is a route break near Delavan.) Business Loop I-76 is concurrent with other U.S. routes (U.S. 34 Fort Morgan to Brush, U.S. 6 to Sterling). It is very odd to see Business Loop I-76 and U.S. 6 shields well signed through miles of corn fields between Fort Morgan and Sterling, but it is also really neat too. In fact, new signs were erected in 2003 along this route. Click here for more information. |
| NEW JERSEY
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| Camden
| Active/Unsigned
| Interstate 76C connects Interstate 76 with U.S. 130 and New Jersey State Route 168. It is freeway-grade, and it serves to funnel traffic to the Walt Whitman Bridge and Philadelphia. There are no I-76C signs on this route, just signs directing travelers to Interstate 76 and 676. |
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